Curiosity guides : the human genome / John Quackenbush.

Includes bibliographical references and index.

Introduction: a race to the future -- A brief history of the genome project -- About the map -- Back to basics -- Mendel's garden: setting the stage -- Darwin's natural selection -- Cells: a hidden universe -- Chromosomes and genetic traits -- Human chromosomes -- DNA: the molecule of heredity -- The central dogma of molecular biology -- DNA to RNA to protein -- Gene mapping and sequencing before the HGP -- Of mice and men, and other creatures -- Bacteria -- Escherichia coli -- Haemophaleus influenzae -- Brewer's yeast: saccharomyces cerevisiae -- Roundworm: Caenorhabditis elegans -- Fruit fly: Drosophila melanogaster -- Human: Homo sapiens -- The next wave of HGPs -- A genome grab bag -- Plants: genome giants -- Miscellaneous mammals -- The unseen world -- Reading the book of life -- Take a look at yourself -- What's in a number? -- Linking genes to traits and functions -- Mutation: in the eye of the beholder? -- Population genomics: something for everyone -- Gene regulation and expression -- Genomics applied: tackling cancer -- What is cancer? -- Linking genes and cancer -- Surveying gene expression -- Using microarrays in cancer study -- Cancer, many diseases -- Toward personalized cancer care -- Cancer viruses and vaccines -- The future of cancer therapy -- Genes and the roots of disease -- Beyond mendel: modern genetics -- Huntington's disease: an autosomal dominant disease -- Cystic fibrosis: an autosomal recessive disease -- Diabetes: a polygenic, multifactorial disease -- Genes, environment, or both? -- Genetics and infectious disease -- It takes a village: social environments and disease -- Personalized medicine -- Systems biology: more than the sum of our parts -- The genomics of evolution -- Out of Africa: genomic diversity -- Y chromosomal adam -- Mitochondrial Eve -- Neanderthals: our lost cousins -- Are we the third chimpanzee? -- A brave new genomic world -- Forensic genomics -- Genomes 'r' us -- Learning from Watson's genome -- Stem cells -- A word about cloning -- Prenatal testing and gene therapy -- Legal and ethical concerns -- Our genomic future.